Reasons for choosing our testing services
ZHONGXI Testing has obtained inspection qualification certifications from multiple countries and regions worldwide. We possess a senior testing team and advanced testing methods, providing independent, impartial, and professional third-party verification services for global carbon projects.
Internationally recognized authority
Certified by multiple international standards such as CNAS, VCS, and GS, with reports universally applicable worldwide.
Global service capability
Covering 140+ countries and regions, it supports on-site detection and remote verification in multiple languages.
Professional experimental methods
Adopt standard experimental methods to ensure accurate and reliable data.
Unmatched Technical Depth: What Our Chromosome Testing Achieves
We go far beyond conventional karyotyping. Our laboratory employs next-generation sequencing (NGS) at ultra-deep coverage (≥30X) and high-density chromosomal microarrays (CMA) with >2.6 million probes to detect copy number variations (CNVs) as small as 5‑10 kb – far exceeding the resolution of standard clinical tests. For prenatal cases, our non‑invasive prenatal testing (NIPT) analyzes cell‑free DNA (cfDNA) with a read depth >100 million unique reads, enabling the detection of whole‑chromosome aneuploidies, segmental imbalances, triploidies, and microdeletions with >99.9% specificity. For postnatal and product of conception (POC) samples, we offer optical genome mapping (OGM) and whole‑exome sequencing (WES) backbone to identify balanced translocations, inversions, and even low‑level mosaicism down to 5% allelic fraction. You receive a comprehensive, clinically actionable report – no blind spots.
Comprehensive Detection Panel: Abnormalities We Identify
The table below lists the major classes of chromosomal abnormalities our test reliably detects, along with representative syndromes.
| Abnormality Category | Examples (Syndromes / Findings) | Our Detection Resolution |
|---|---|---|
| Numerical aneuploidies | Trisomy 21 (Down), Trisomy 18 (Edwards), Trisomy 13 (Patau), Monosomy X (Turner), XXY (Klinefelter), XYY, Triploidy | ≥99.9% sensitivity, 0.1% false positive rate |
| Sex chromosome abnormalities | 45,X/46,XY mosaicism, 47,XXX, 48,XXYY, etc. | Detects mosaicism ≥5% |
| Microdeletions / microduplications | 22q11.2 (DiGeorge), 1p36 deletion, Cri‑du‑chat (5p‑), 16p11.2, 15q11.2 (Prader‑Willi/Angelman) | ≥5‑10 kb resolution (CMA/NGS) |
| Segmental imbalances | Partial trisomies, interstitial deletions, duplications >200 kb | 100% detection for >200 kb; partial for smaller clinically relevant CNVs |
| Balanced rearrangements | Reciprocal translocations, Robertsonian translocations, inversions | Detected by OGM and karyotyping (available add‑on) |
| Low‑level mosaicism & confined placental mosaicism (CPM) | Mosaic trisomy 8, mosaic Turner, etc. | Detected down to 5% abnormal cell line |
All positive findings are confirmed by an orthogonal method (FISH or qPCR) before release, ensuring zero false reports for actionable anomalies.
Why Choose Our Chromosome Abnormality Testing Service?
We understand that a genetic test result can change lives. That’s why we have built a service that prioritizes accuracy, speed, and comprehensive support. Our key advantages include:
1. CLIA‑certified and CAP‑accredited laboratory – operating under the highest quality standards with routine participation in external proficiency testing (e.g., CAP/ACMG surveys).
2. Rapid turnaround time – NIPT results in 5‑7 calendar days; postnatal CMA/NGS in 7‑10 business days; urgent cases expedited upon request.
3. Pre‑ and post‑test genetic counseling – every test includes a complimentary session with a board‑certified genetic counselor to help you interpret results and plan next steps.
4. Transparent pricing & insurance assistance – no hidden fees. We verify your insurance coverage upfront and offer self‑pay options starting at $249 for core NIPT (financial aid available).
5. Global sample shipping – we provide prepaid, temperature‑controlled collection kits and coordinate with a network of phlebotomists worldwide.
6. Advanced bioinformatics pipeline – our proprietary algorithm, ChromoSure™ AI, integrates population frequency databases (gnomAD, DGV, ClinVar) to reduce variants of uncertain significance (VUS) and improve clinical concordance.
We do not just give you a list of gains and losses – we provide a clinical interpretation table, management recommendations, and direct access to our lab directors for complex cases.
Take Control of Your Genetic Health – Order Your Test Today
Whether you are a parent, a soon‑to‑be parent, or an individual with unexplained symptoms, our chromosome abnormality test is available by direct patient request (with optional physician referral). Start by completing our simple online intake form, and a testing coordinator will reach out within 24 hours to arrange sample collection and answer all your questions. No waiting lists – no unnecessary delays. Call us at 1-888-566-4636 or email care@chromotest.com to initiate your testing journey. Your answers matter, and we are here to find them with unparalleled precision.