Antioxidant and In Vitro Efficacy Testing Services

Antioxidant and In Vitro Efficacy Testing Services

An internationally recognized testing institution, assisting enterprises in achieving technological advancement.

Reasons for choosing our testing services

ZHONGXI Testing has obtained inspection qualification certifications from multiple countries and regions worldwide. We possess a senior testing team and advanced testing methods, providing independent, impartial, and professional third-party verification services for global carbon projects.

Internationally recognized authority

Internationally recognized authority

Certified by multiple international standards such as CNAS, VCS, and GS, with reports universally applicable worldwide.

Global service capability

Global service capability

Covering 140+ countries and regions, it supports on-site detection and remote verification in multiple languages.

Professional experimental methods

Professional experimental methods

Adopt standard experimental methods to ensure accurate and reliable data.

For procurement and quality teams, defining a clear scope for testing saves significant time and ensures alignment with project requirements. Our antioxidant and in vitro efficacy testing services are designed to demonstrate the performance and reliability of materials under standardized conditions. This page outlines the testing scope, parameters, and data analysis methodologies to help clients understand our capabilities and select the appropriate services for their needs.

Testing Scope

Our antioxidant and in vitro efficacy testing covers a wide range of products, including polymers, coatings, lubricants, and specialty chemicals. The testing is applicable to various materials, such as polyethylene, polypropylene, epoxy resins, and synthetic rubbers. Different grades and formulations can be assessed based on client specifications, with common applications including automotive components, industrial parts, and medical devices. The testing aligns with internationally recognized standards such as ASTM, ISO, EN, and GB, ensuring global compliance and interoperability.

Application scenarios include assessing the resistance of materials to oxidative degradation, evaluating the effectiveness of antioxidants in preserving material integrity, and verifying in vitro performance under simulated environmental conditions. The testing is particularly relevant for industries where material longevity and performance under stress are critical, such as aerospace, electronics, and healthcare.

Testing Items and Parameters

The testing items and parameters are designed to measure the antioxidant properties and in vitro efficacy of materials. Key test methods include oxidative induction temperature (OIT), Thermogravimetric Analysis (TGA), and differential scanning calorimetry (DSC). In vitro efficacy is evaluated through methods like cell viability assays, Cytotoxicity tests, and degradation rate measurements. Typical parameters and graded limit requirements are detailed below:

Test Item Typical Parameters Graded Limit Requirements
Oxidative Induction Temperature (OIT) Temperature range: 150°C - 300°C Minimum OIT: 200°C for general applications; higher for critical uses
Thermogravimetric Analysis (TGA) Weight loss percentage at 500°C Maximum weight loss: 5% for high-performance materials
Differential Scanning Calorimetry (DSC) Heat flow rate and transition temperatures Consistent transition points within ±2°C of initial values
Cell Viability Assays MTT assay, LDH release assay Viability > 90% for non-cytotoxic materials
Cytotoxicity Tests ALDH activity, ROS production No significant toxicity at concentrations up to 100 μg/mL

Additional parameters can be included based on specific client requirements, such as moisture resistance, UV stability, or chemical compatibility tests. The graded limits are set to ensure materials meet industry benchmarks and regulatory requirements.

Data and Variation Analysis

Parallel-sample and batch-to-batch variation are rigorously assessed to ensure reproducibility and consistency. For parallel-sample analysis, relative deviation between replicates is calculated using standard statistical methods. Typically, test results show a relative deviation of ≤5% for most parameters, with critical tests requiring tighter tolerances of ≤2%. Batch-to-batch variation is evaluated by comparing results from consecutive production runs, with acceptance windows defined based on historical data and material specifications.

The variation analysis includes mean, standard deviation, and confidence intervals to quantify performance consistency. Deviations outside the acceptance window are investigated to identify root causes, such as raw material fluctuations or process variations. The final report provides a comprehensive analysis of variation, including graphical representations of data trends and statistical summaries to support decision-making.

For clients seeking detailed testing services, we invite you to share drawings, material grades, or purchase specifications. This information allows us to match the testing plan precisely to your requirements, ensuring accurate and relevant results. Contact our technical team to discuss your specific needs and receive a customized testing proposal.

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About Us

Beijing ZKGX Institute of Science and Technology , combining applied research with technological transformation. It has evolved into a comprehensive research institute characterized primarily by a "task-driven disciplines" approach. Approved by relevant authorities, it currently operates as a third-party analytical testing technical service provider. Its affiliated laboratory facilities hold certifications including CMA and CNAS, possess an Experimental Animal Use License, and have achieved triple certification for ISO9001 Quality Management System, ISO14001 Environmental Management System, and ISO45001 Occupational Health and Safety Management System.