Reasons for choosing our testing services
ZHONGXI Testing has obtained inspection qualification certifications from multiple countries and regions worldwide. We possess a senior testing team and advanced testing methods, providing independent, impartial, and professional third-party verification services for global carbon projects.
Internationally recognized authority
Certified by multiple international standards such as CNAS, VCS, and GS, with reports universally applicable worldwide.
Global service capability
Covering 140+ countries and regions, it supports on-site detection and remote verification in multiple languages.
Professional experimental methods
Adopt standard experimental methods to ensure accurate and reliable data.
Selecting a testing partner begins with understanding the scope of analysis available. For clients seeking precise and reliable Nisin Z testing, our laboratory offers capabilities aligned with global regulatory requirements. We serve industries requiring microbial preservatives, food additives, and pharmaceutical excipients, ensuring accurate measurement and characterization of Nisin Z.
Testing Scope
Our Nisin Z testing services cover a range of products, materials, and applications. Applicable products include food preservatives, dairy products, pharmaceuticals, and biotechnological formulations. Materials tested encompass liquid concentrates, dry powders, and finished products containing Nisin Z as an active ingredient. Grades analyzed range from industrial-grade to food-grade standards, with applications in food preservation, antimicrobial coatings, and medical applications. Commonly referenced standards include ISO 17451 (Determination of Nisin), FDA guidelines (Code of Federal Regulations 21 CFR), and EFSA specifications for food additives.
Testing Items and Parameters
The following test items and parameters are conducted for Nisin Z analysis:
- Nisin Z quantification (µg/g or IU/g)
- purity assessment (HPLC, mass spectrometry)
- antimicrobial activity (minimal inhibitory concentration)
- stability testing (shelf life, temperature effects)
- residual solvent analysis (ICH guidelines)
Typical parameter limits and requirements are outlined in the table below:
| Test Item | Typical Parameter | Graded Limit |
|---|---|---|
| Nisin Z quantification | Concentration (µg/g) | ≥ 90% (food grade), ≥ 98% (pharma grade) |
| Purity (HPLC) | Peak area percentage | ≥ 95% |
| Antimicrobial activity | MIC (µg/mL) | |
| Residual solvents | Peak area percentage |
Additional tests may be performed based on client requirements, such as heavy metal content (ISO 17516) or Endotoxin levels (ISO 14644).
Data and Variation Analysis
Parallel-sample and batch-to-batch variation are rigorously assessed using statistical methods. For parallel-sample analysis, relative deviation between duplicates is calculated using the formula:
Relative Deviation (%) = (Sample 1 - Sample 2) / Average × 100%
Acceptance windows are established based on historical data, typically within ±5% for quantification and ±10% for purity assessments. Batch-to-batch variation is analyzed using coefficient of variation (CV) and ANOVA (Analysis of Variance), ensuring consistent product quality. Results are reported with confidence intervals (95%), and standard deviation limits are specified for each parameter. The capability of the method is demonstrated through precision, linearity (R² ≥ 0.99), and accuracy (recovery 90-110%) as per ISO 17025 requirements.
Send us your testing item list and sample details, and our engineers will confirm the applicable items and turnaround within one working day.